| Pathway |
Reactome pathway entity representing a curated biological pathway or reaction... |
no |
| CellularComponent |
Gene Ontology Cellular Component term |
no |
| DiseaseOrPhenotype |
Abstract parent class for all disease/phenotype entities |
no |
| VariantDiseaseAssociation |
Optional association for Variant -> Disease when variant-level evidence, clin... |
no |
| Protein |
Protein product (UniProt model) |
no |
| ExposureDiseaseAssociation |
Optional association for ExposureOrStressor -> Disease when epidemiology, mec... |
no |
| TranscriptionFactorRegulationAssociation |
Optional association for TranscriptionFactor -> Gene when direction, confiden... |
no |
| DiseaseSubtype |
Molecularly-defined disease subtype derived from clustering analysis (transcr... |
no |
| Association |
Abstract base for optional evidence-bearing associations |
no |
| BiologicalProcess |
Gene Ontology Biological Process term |
no |
| VariantProteinEffectAssociation |
Optional association for Variant -> Protein when protein consequence, predict... |
no |
| Gene |
Human gene entity (Entrez/NCBI model) |
no |
| DrugTargetAssociation |
Optional association for Drug -> MolecularEntity when action type, binding af... |
no |
| GeneDiseaseAssociation |
Optional association for Gene -> Disease when causal/risk/protective or corre... |
no |
| Drug |
Pharmaceutical compound (DrugBank model) |
no |
| Disease |
Disease entity |
no |
| NamedEntity |
Root class for all named entities in the ALS-KG ontology |
no |
| DrugDiseaseTherapeuticAssociation |
Optional association for Drug -> Disease when therapeutic indication, approva... |
no |
| TranscriptionFactor |
Gene encoding a transcription factor (TF) |
no |
| ProteinPathwayAssociation |
Optional association for Protein -> Pathway when Reactome evidence code, sour... |
no |
| BiologicalConcept |
Abstract base for functional/biological concepts from GO and related ontologi... |
no |
| MolecularFunction |
Gene Ontology Molecular Function term |
no |
| ProteinProteinInteractionAssociation |
Optional association for Protein -> Protein when interaction score, interacti... |
no |
| Variant |
Genetic sequence variant (ClinVar model) |
no |
| OntologyClass |
Abstract base for entity classes (nodes in knowledge graph) |
no |
| Anatomy |
Anatomical structure (UBERON ontology) |
no |
| DiseasePhenotypeAssociation |
Optional association for Disease -> Phenotype when the clinical feature requi... |
no |
| Phenotype |
Phenotypic feature (HPO term) |
no |
| ExposureOrStressor |
Environmental exposure or chemical stressor from CTD ontology |
no |
| ChemicalEntity |
Abstract base for chemical and pharmacological entities (drugs, exposures, me... |
no |
| GeneExpressionAssociation |
Optional association for Gene -> Anatomy when expression level, specificity, ... |
no |
| MolecularEntity |
Abstract base for molecular-level entities (genes, proteins, variants) |
no |
| DiseaseDiseaseAssociation |
Optional association for Disease -> Disease when disease-disease edges need r... |
no |