Class: ReferenceTherapeutic
Reference identity for a therapeutic or intervention-oriented entity.
URI: reactome:ReferenceTherapeutic
classDiagram
class ReferenceTherapeutic
click ReferenceTherapeutic href "../ReferenceTherapeutic/"
ReferenceEntity <|-- ReferenceTherapeutic
click ReferenceEntity href "../ReferenceEntity/"
ReferenceTherapeutic : created
ReferenceTherapeutic --> "1" InstanceEdit : created
click InstanceEdit href "../InstanceEdit/"
ReferenceTherapeutic : definition
ReferenceTherapeutic : description
ReferenceTherapeutic : display_label
ReferenceTherapeutic : has_reference_database
ReferenceTherapeutic --> "1" ReferenceDatabase : has_reference_database
click ReferenceDatabase href "../ReferenceDatabase/"
ReferenceTherapeutic : id
ReferenceTherapeutic : identifier
ReferenceTherapeutic : modified
ReferenceTherapeutic --> "*" InstanceEdit : modified
click InstanceEdit href "../InstanceEdit/"
ReferenceTherapeutic : name
ReferenceTherapeutic : previous_stable_identifier
ReferenceTherapeutic : reactome_db_id
ReferenceTherapeutic : reactome_stable_identifier
ReferenceTherapeutic : source_schema_class
Inheritance
- NamedEntity
- DatabaseObject
- ReferenceEntity
- ReferenceTherapeutic
- ReferenceEntity
- DatabaseObject
Class Properties
| Property | Value |
|---|---|
| Class URI | reactome:ReferenceTherapeutic |
Slots
| Name | Cardinality and Range | Description | Inheritance |
|---|---|---|---|
| has_reference_database | 1 ReferenceDatabase |
Reference database authority associated with a reference entity or database i... | ReferenceEntity |
| identifier | 0..1 String |
Identifier string assigned by an external reference database | ReferenceEntity |
| reactome_db_id | 1 Integer |
Internal Reactome database identifier assigned to a database object | DatabaseObject |
| reactome_stable_identifier | 1 String |
Stable public Reactome identifier for an object | DatabaseObject |
| source_schema_class | 1 String |
Name of the source Reactome schema class from which the instance derives | DatabaseObject |
| display_label | 1 String |
Preferred display label used by Reactome for user-facing presentation | DatabaseObject |
| definition | 0..1 String |
Curated textual definition that states what the object is | DatabaseObject |
| previous_stable_identifier | 0..1 String |
Deprecated or previous stable Reactome identifier retained for traceability | DatabaseObject |
| created | 1 InstanceEdit |
Provenance link to the curation event that originally created the object reco... | DatabaseObject |
| modified | * InstanceEdit |
Provenance links to subsequent modifications of the object record | DatabaseObject |
| id | 1 String |
Unique identifier for an instance in the serialized dataset | NamedEntity |
| name | 0..1 String |
Human-readable primary label for an object | NamedEntity |
| description | 0..1 String |
Free-text textual description of an object | NamedEntity |
Comments
- Supports the reference-layer counterpart of drug-like modeled entities.
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/reactome-ontology
Mappings
| Mapping Type | Mapped Value |
|---|---|
| self | reactome:ReferenceTherapeutic |
| native | reactome:ReferenceTherapeutic |
LinkML Source
Direct
name: reference_therapeutic
description: Reference identity for a therapeutic or intervention-oriented entity.
comments:
- Supports the reference-layer counterpart of drug-like modeled entities.
from_schema: https://w3id.org/reactome-ontology
is_a: reference_entity
class_uri: reactome:ReferenceTherapeutic
Induced
name: reference_therapeutic
description: Reference identity for a therapeutic or intervention-oriented entity.
comments:
- Supports the reference-layer counterpart of drug-like modeled entities.
from_schema: https://w3id.org/reactome-ontology
is_a: reference_entity
attributes:
has_reference_database:
name: has_reference_database
description: Reference database authority associated with a reference entity or
database identifier.
comments:
- Provides the namespace and interpretation context for an identifier.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:hasReferenceDatabase
alias: has_reference_database
owner: reference_therapeutic
domain_of:
- reference_entity
- database_identifier
range: reference_database
required: true
multivalued: false
identifier:
name: identifier
description: Identifier string assigned by an external reference database.
comments:
- Examples include UniProt accessions, ChEBI identifiers, or GO term identifiers.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:identifier
alias: identifier
owner: reference_therapeutic
domain_of:
- reference_entity
- database_identifier
range: string
multivalued: false
reactome_db_id:
name: reactome_db_id
description: Internal Reactome database identifier assigned to a database object.
comments:
- Reactome DB_ID values are implementation-oriented identifiers rather than stable
public identifiers.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:reactomeDbId
alias: reactome_db_id
owner: reference_therapeutic
domain_of:
- database_object
range: integer
required: true
multivalued: false
reactome_stable_identifier:
name: reactome_stable_identifier
description: Stable public Reactome identifier for an object.
comments:
- Typically corresponds to the curated Reactome stable accession such as R-HSA-xxxxx.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:reactomeStableIdentifier
alias: reactome_stable_identifier
owner: reference_therapeutic
domain_of:
- database_object
range: string
required: true
multivalued: false
source_schema_class:
name: source_schema_class
description: Name of the source Reactome schema class from which the instance
derives.
comments:
- Useful when preserving frame-schema provenance or round-tripping with the original
Reactome graph.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:sourceSchemaClass
alias: source_schema_class
owner: reference_therapeutic
domain_of:
- database_object
range: string
required: true
multivalued: false
display_label:
name: display_label
description: Preferred display label used by Reactome for user-facing presentation.
comments:
- Often combines identity and contextual state into a concise label.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
is_a: name
slot_uri: reactome:displayLabel
alias: display_label
owner: reference_therapeutic
domain_of:
- database_object
range: string
required: true
multivalued: false
definition:
name: definition
description: Curated textual definition that states what the object is.
comments:
- Intended for conceptual definitions rather than narrative summaries.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:definition
alias: definition
owner: reference_therapeutic
domain_of:
- database_object
range: string
multivalued: false
previous_stable_identifier:
name: previous_stable_identifier
description: Deprecated or previous stable Reactome identifier retained for traceability.
comments:
- Useful during migration, identifier replacement, and legacy resolution.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:previousStableIdentifier
alias: previous_stable_identifier
owner: reference_therapeutic
domain_of:
- database_object
range: string
multivalued: false
created:
name: created
description: Provenance link to the curation event that originally created the
object record.
comments:
- Usually points to an InstanceEdit containing editor and date metadata.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:created
alias: created
owner: reference_therapeutic
domain_of:
- database_object
range: instance_edit
required: true
multivalued: false
modified:
name: modified
description: Provenance links to subsequent modifications of the object record.
comments:
- Multiple modifications are common across curation history.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: reactome:modified
alias: modified
owner: reference_therapeutic
domain_of:
- database_object
range: instance_edit
multivalued: true
id:
name: id
description: Unique identifier for an instance in the serialized dataset.
comments:
- This may be a local identifier, CURIE, URI, or other serialization key.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: dcterms:identifier
identifier: true
alias: id
owner: reference_therapeutic
domain_of:
- named_entity
range: string
required: true
name:
name: name
description: Human-readable primary label for an object.
comments:
- Generic reusable naming slot for schema-wide use.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: rdfs:label
alias: name
owner: reference_therapeutic
domain_of:
- named_entity
range: string
description:
name: description
description: Free-text textual description of an object.
comments:
- Can hold editorial notes, plain-language explanations, or short summaries.
from_schema: https://w3id.org/reactome-ontology
rank: 1000
slot_uri: dcterms:description
alias: description
owner: reference_therapeutic
domain_of:
- named_entity
range: string
multivalued: false
class_uri: reactome:ReferenceTherapeutic